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Code 49 means the payer classified the service as a routine exam or screening the plan doesn't cover in this context — and the PR prefix puts the balance on the patient. Here's when that's right, and when it's a coding problem you can fix.
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Code 49's official text: "This is a non-covered service because it is a routine/preventive exam or a diagnostic/screening procedure done in conjunction with a routine/preventive exam." Translation: the payer decided this was routine care — an annual physical, a screening test without symptoms — and the patient's plan doesn't cover that service, or doesn't cover it in this combination. With the PR prefix, the balance is patient responsibility and can be billed to them; but before any statement goes out, verify the claim was coded correctly — because the routine-vs-diagnostic line is one of the most commonly miscoded distinctions in billing.
Related: PR-204 — not a covered benefit · CO-96 — non-covered charges · Modifier 25 guide · Full library
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