What CO-45 means on your remittance, exactly how to fix it, and the appeal language that gets it overturned.
Free CO-45 appeal letter template. Scroll to CO-45 Appeal Letter Template below for wording you can copy, or generate a complete CO-45 appeal letter with our free tool — it fills in the payer, dates and policy references for you.
CO-45 means the amount you billed is higher than the payer's contracted or allowed amount for that service. The difference is a contractual adjustment — the payer is telling you to write it off, and in-network providers cannot bill the patient for it.
Code group: CO (Contractual Obligation) · Appealable: Only when the allowed amount is below your contracted rate. Routine CO-45 contractual adjustments are not appealable — they are the normal difference between charges and contracted rates.
Here is how CO-45 shows up on a real Medicare claim. Say a practice bills $150 for a 99213 office visit in 2026. The national Medicare allowed amount for 99213 in an office is $95.19, and the patient has already met the deductible.
| Line on the remittance | Amount | What it means |
|---|---|---|
| Billed charge | $150.00 | Your fee for the visit |
| CO-45 adjustment | $54.81 | Charge minus the allowed amount. You write this off. |
| Allowed amount | $95.19 | The 2026 national Medicare rate for 99213 (office) |
| PR-2 coinsurance | $19.04 | The patient owes 20% of the allowed amount |
| CO-253 sequestration | $1.52 | The 2% federal cut taken from Medicare's share |
| Medicare payment | $74.63 | 80% of the allowed amount, less 2% |
The lines add back up to the $150 charge: $54.81 + $19.04 + $1.52 + $74.63. If the deductible was not met, part of the allowed amount shows as PR-1 instead of being paid.
How to check yours. Look up the allowed amount for your code and area in our Medicare fee lookup. If Medicare allowed less than that, or a commercial plan allowed less than your contract, it is an underpayment, not a normal CO-45. If you are not a participating Medicare provider, Medicare allows 95% of the fee schedule amount.
Watch for a CO-45 of zero. Medicare pays the lower of your charge or the fee schedule. If your charge is below the allowed amount, there is no CO-45 and you are paid your own lower charge. A zero CO-45 on a common code usually means your fee schedule is set too low.
Source: CMS Physician Fee Schedule, 2026 RVU file (conversion factor $33.4009).
Adapt this wording to your claim — replace the bracketed fields and attach the documentation it references:
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Reviewed by the LegitMedBilling denial management team. This guide is general billing information, not legal or payer-specific advice — always verify against your payer contract and current policy.
Reviewed by Hassan Raza Awan, Founder — 4+ years of hands-on U.S. medical billing experience. General billing information — verify against current CMS guidance and your payer contracts.
Free tool: Underpayment Calculator — CO-45 is the contractual adjustment, not an underpayment. Check whether the allowed amount matched your contract.
CO-45 is the write-off between charge and allowed amount. What is the allowed amount explains where that figure comes from and why it is not billable to the patient.
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